Copenhagen Plant Science Centre PhD Summer Course
Synthetic biology is the engineering of biology: the deliberate (re)design and construction of novel biological and biologically based parts, devices and systems to perform new functions for useful purposes, that draws on principles elucidated from biology and engineering.
In this context prokaryotic and eukaryotic organisms like bacteria (e.g. B. subtilis or E.coli), yeast, microalgae or plants are interesting since they hold the promise for truly sustainable production of high-value compounds like pharmaceutical, commodity chemicals or even fuels. Traditionally the organisms of choice for synthetic biology have been E. coli and yeast. However, in the future synthetic biology in plant science will have a great potential both for redirecting and engineering of new biosynthetic pathways as well as for improving yield of our crop plants. In this field, the University of Copenhagen is among the leading institutions.
- Choice of organisms (chassis): (cyano-) bacteria (B. subtilis, E.coli, Synechocystis), yeast, algae, higher plants (chloroplasts).
- The parts: Promoters for regulated expression, transcript and protein stabilization and modifications, vectors, neutral integration, DNA synthesis, flip elements for on-off gene expression regulation.
- Cloning and high-through-put methodologies: cloning methods, gene stacking, gene replacements.
- Bioreactors: types (closed, open ponds, etc.), designs of growth regimes (continuous versus batch), harvesting methods and product recovery.
- Downstream processing: product extraction, stabilization and quality control
- Ethics in synthetic biology.
- Safety and regulations.
- Intellectual property rights (IPR)
Price: 1500 DKK. Lunch and coffee/tea is included.
Registration: To register for the course please fill in the registration form and send to Lene Rasmussen firstname.lastname@example.org